Zika Virus Alert: Dr. S. Balasubramanian .
Zika is a Flavi viridiae of RNA Virus. Belongs to Dengue, Chikungunya,West Neile, J.E Yellow fever groups.
At present outbreak at Brazil - America.
Mosquito born -Aedes agypti.
Cardinal symptoms - Hyperpyrexia, Body ache , Conjuctivitis( Not seen in Dengue & Chik) Rhases.
Mild form - Not a Mortality disease.
Pathogenesis - Immediate after a bite of mosquito it infect Dendritic cell then to Lymph Node to Blood stream.
Incubation period 2 to 14 days.
Public Health importance --
1. Not a Mortality Disease.
2. Mid form not like dengue.
3. Self limitting. Pt. recoverd in 7 days.
4. Only symptomatic management - Rehydration, Antipyretic .
5. Complication - post infection GBS. & Microcephaly (infection in 1st trimster.)
6. This cogenital anamoly possibly the virus replicate in the nucleous of the infected
Cells. Other flavi viruses replicate in the Cytoplasm.
7. No transoverian transmission in mosquito.
8. So Pregnant mothers in early pergnancy avoid travel to America.
9. No Specific Vaccine & Drug.
10. Transmission also by Sexual route. ( Virus Isolated in Semen).
Prevention :
1. Restrict travel to America.
2. No travel in Early pregnancy.
3. Any individuals from Amerca will be watched for fever upto14 days.
4. Devevoloped fever inform District / Local Health Authorities.
5. Keep mosquito free enviornment.
6. Not to use plastic cups & carry bags.
